# Comparison of the Outcome of Treatment With Silymarin or N-Aceylcysteine in Patients Taking Anti-Tuberculous Drugs for Tuberculosis at a Tertiary Care Hospital , Karachi

> **NCT07058090** · PHASE1 · NOT_YET_RECRUITING · sponsor: **Liaquat National Hospital & Medical College** · enrollment: 410 (estimated)

## Conditions studied

- Drug Induced Liver Injury
- Tuberculosis (TB)

## Interventions

- **DRUG:** Silymarin 420 mg
- **DRUG:** N Acetyl Cysteine
- **DRUG:** Rifampicin (RMP) Ethambutol (E) Isoniazid (H) Pyrazinamid (Z)

## Key facts

- **NCT ID:** NCT07058090
- **Lead sponsor:** Liaquat National Hospital & Medical College
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2025-07
- **Primary completion:** 2025-12
- **Final completion:** 2026-05
- **Target enrollment:** 410 (ESTIMATED)
- **Last updated:** 2025-07-10


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07058090

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07058090, "Comparison of the Outcome of Treatment With Silymarin or N-Aceylcysteine in Patients Taking Anti-Tuberculous Drugs for Tuberculosis at a Tertiary Care Hospital , Karachi". Retrieved via AI Analytics 2026-06-03 from https://api.ai-analytics.org/clinical/NCT07058090. Licensed CC0.

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