# Optimizing Portal Hypertension With TIPS and Interval Metabolic Surgery for Advanced Liver Disease

> **NCT07058155** · PHASE4 · RECRUITING · sponsor: **The Cleveland Clinic** · enrollment: 70 (estimated)

## Conditions studied

- Liver Cirrhoses
- Portal Hypertension Related to Cirrhosis
- Severe Obesity
- TIPS

## Interventions

- **PROCEDURE:** Transjugular Intrahepatic Portosystemic Shunt (TIPS)
- **PROCEDURE:** Sleeve Gastrectomy
- **DRUG:** Anti-Obesity Pharmacotherapy (Class Effect)
- **BEHAVIORAL:** Lifestyle Counseling - Diet & Physical-Activity Program

## Key facts

- **NCT ID:** NCT07058155
- **Lead sponsor:** The Cleveland Clinic
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-12-17
- **Primary completion:** 2029-02-01
- **Final completion:** 2034-02-01
- **Target enrollment:** 70 (ESTIMATED)
- **Last updated:** 2025-12-23

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07058155

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07058155, "Optimizing Portal Hypertension With TIPS and Interval Metabolic Surgery for Advanced Liver Disease". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT07058155. Licensed CC0.

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