# Mesothelin and Claudin 18.2 Dual-Target CAR-T Therapy in Advanced Pancreatic Cancer

> **NCT07066995** · PHASE1,PHASE2 · RECRUITING · sponsor: **Essen Biotech** · enrollment: 60 (estimated)

## Conditions studied

- Pancreatic Cancer
- Pancreatic Carcinoma
- Pancreatic Cancer Non-resectable
- Pancreatic Cancer Stage IV

## Interventions

- **BIOLOGICAL:** Mesothelin and Claudin 18.2 CAR-T cells

## Key facts

- **NCT ID:** NCT07066995
- **Lead sponsor:** Essen Biotech
- **Sponsor class:** OTHER
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-04-29
- **Primary completion:** 2027-12-10
- **Final completion:** 2028-12-28
- **Target enrollment:** 60 (ESTIMATED)
- **Last updated:** 2025-07-15


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07066995

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07066995, "Mesothelin and Claudin 18.2 Dual-Target CAR-T Therapy in Advanced Pancreatic Cancer". Retrieved via AI Analytics 2026-07-18 from https://api.ai-analytics.org/clinical/NCT07066995. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*