# A Clinical Study to Test if an Investigational Treatment Called BNT314 When Used in Combination With Another Investigational Treatment BNT327 and Chemotherapy, is Beneficial and Safe for Patients With Advanced Colorectal Cancer

> **NCT07079631** · PHASE1,PHASE2 · RECRUITING · sponsor: **BioNTech SE** · enrollment: 482 (estimated)

## Conditions studied

- Metastatic Colorectal Cancer

## Interventions

- **BIOLOGICAL:** BNT314
- **DRUG:** BNT327
- **DRUG:** SoC chemotherapy treatment 1
- **DRUG:** SoC chemotherapy treatment 2
- **DRUG:** Bevacizumab

## Key facts

- **NCT ID:** NCT07079631
- **Lead sponsor:** BioNTech SE
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-07-18
- **Primary completion:** 2030-12
- **Final completion:** 2031-05
- **Target enrollment:** 482 (ESTIMATED)
- **Last updated:** 2026-04-17

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07079631

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07079631, "A Clinical Study to Test if an Investigational Treatment Called BNT314 When Used in Combination With Another Investigational Treatment BNT327 and Chemotherapy, is Beneficial and Safe for Patients With Advanced Colorectal Cancer". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT07079631. Licensed CC0.

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