# EMG-Based Evaluation of Occlusal Splint and Masseter Botox Effects on Head and Neck Muscles

> **NCT07082972** · PHASE4 · RECRUITING · sponsor: **Istanbul University** · enrollment: 56 (estimated)

## Conditions studied

- Myofascial Pain Syndrome (MPS)
- Masticatory Muscle Pain

## Interventions

- **DRUG:** Botulinum toxin injection
- **DEVICE:** Occlusal splint
- **COMBINATION_PRODUCT:** Botulinum toxin + Occlusal splint combined

## Key facts

- **NCT ID:** NCT07082972
- **Lead sponsor:** Istanbul University
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-09-01
- **Primary completion:** 2026-09-01
- **Final completion:** 2026-12-01
- **Target enrollment:** 56 (ESTIMATED)
- **Last updated:** 2025-07-24


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07082972

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07082972, "EMG-Based Evaluation of Occlusal Splint and Masseter Botox Effects on Head and Neck Muscles". Retrieved via AI Analytics 2026-06-03 from https://api.ai-analytics.org/clinical/NCT07082972. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*