# GLP-1/GCG Dual Agonist in Type 2 Diabetes With Early Dementia (LIGHT-COG Study)

> **NCT07083154** · PHASE3 · RECRUITING · sponsor: **The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School** · enrollment: 420 (estimated)

## Conditions studied

- Dementia, Mild
- Mild Cognitive Impairment
- Type 2 Diabetes

## Interventions

- **DRUG:** Mazdutide
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT07083154
- **Lead sponsor:** The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-09-27
- **Primary completion:** 2029-08-01
- **Final completion:** 2029-08-01
- **Target enrollment:** 420 (ESTIMATED)
- **Last updated:** 2026-03-05

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07083154

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07083154, "GLP-1/GCG Dual Agonist in Type 2 Diabetes With Early Dementia (LIGHT-COG Study)". Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/clinical/NCT07083154. Licensed CC0.

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