# A Study to Learn About How a New Pneumococcal Vaccine Works in Adults

> **NCT07086677** · PHASE1 · ACTIVE_NOT_RECRUITING · sponsor: **Pfizer** · enrollment: 380 (actual)

## Conditions studied

- Streptococcus Pneumoniae

## Interventions

- **BIOLOGICAL:** PG4 vaccine in Buffer 1 with low dose PA-001
- **BIOLOGICAL:** PG4 in Buffer 1 with low dose PA-002
- **BIOLOGICAL:** PG4 in Buffer 1 with high dose PA-001
- **BIOLOGICAL:** PG4 vaccine in Buffer 1 with high dose PA-002
- **BIOLOGICAL:** PG4 vaccine in Buffer 2
- **BIOLOGICAL:** 20-valent pneumococcal conjugate vaccine
- **BIOLOGICAL:** Saline injection

## Key facts

- **NCT ID:** NCT07086677
- **Lead sponsor:** Pfizer
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2025-07-22
- **Primary completion:** 2027-10-21
- **Final completion:** 2027-10-21
- **Target enrollment:** 380 (ACTUAL)
- **Last updated:** 2026-04-08


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07086677

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07086677, "A Study to Learn About How a New Pneumococcal Vaccine Works in Adults". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT07086677. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*