# Ex Vivo T-Cell-Depleted Haploidentical Transplantation Bridging With Chimeric Antigen Receptor T-cell Therapy and Prophylactic Memory T Cell Infusion for Acute Leukemia

> **NCT07087847** · NA · NOT_YET_RECRUITING · sponsor: **Ruijin Hospital** · enrollment: 18 (estimated)

## Conditions studied

- Acute Leukemia
- Acute Leukemia Refractory
- Acute Myeloid Leukemia (AML)
- ALL (Acute B-Lymphoblastic Leukemia)
- Acute Leukemia in Relapse

## Interventions

- **BIOLOGICAL:** TCRαβ+/CD45RA+depleted haploidentical hematopoietic stem cell transplantation (haplo-HSCT)

## Key facts

- **NCT ID:** NCT07087847
- **Lead sponsor:** Ruijin Hospital
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2025-09-01
- **Primary completion:** 2028-01-30
- **Final completion:** 2028-09-30
- **Target enrollment:** 18 (ESTIMATED)
- **Last updated:** 2025-07-28

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07087847

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07087847, "Ex Vivo T-Cell-Depleted Haploidentical Transplantation Bridging With Chimeric Antigen Receptor T-cell Therapy and Prophylactic Memory T Cell Infusion for Acute Leukemia". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT07087847. Licensed CC0.

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