# The Perioperative Outcome of Epinephrine Infusion and Tranexamic Acid in Knee Arthroplasty Surgery

> **NCT07089251** · PHASE4 · RECRUITING · sponsor: **King Abdullah International Medical Research Center** · enrollment: 80 (estimated)

## Conditions studied

- Knee Arthroplasty, Total
- Knee Arthritis, Osteoarthritis
- Total Knee Anthroplasty
- Blood Loss
- Tranexamic Acid Use
- Epinephrine

## Interventions

- **DRUG:** low-dose epinephrine and tranexamic acid
- **DRUG:** Tranexamic Acid (TXA) treatment

## Key facts

- **NCT ID:** NCT07089251
- **Lead sponsor:** King Abdullah International Medical Research Center
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-07-15
- **Primary completion:** 2027-06-24
- **Final completion:** 2027-06-24
- **Target enrollment:** 80 (ESTIMATED)
- **Last updated:** 2025-07-28


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07089251

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07089251, "The Perioperative Outcome of Epinephrine Infusion and Tranexamic Acid in Knee Arthroplasty Surgery". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT07089251. Licensed CC0.

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