# Treatment of Inflammatory Myelitis and Optic Neuritis With Early vs Rescue Plasma Exchange (TIMELY-PLEX)

> **NCT07100990** · PHASE3 · RECRUITING · sponsor: **Mayo Clinic** · enrollment: 382 (estimated)

## Conditions studied

- Optic Neuritis
- Myelitis
- Myelitis, Transverse

## Interventions

- **DRUG:** High-dose corticosteroids (HDCS)
- **DRUG:** High-dose corticosteroids (HDCS) and PLEX

## Key facts

- **NCT ID:** NCT07100990
- **Lead sponsor:** Mayo Clinic
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-07-11
- **Primary completion:** 2029-04-01
- **Final completion:** 2031-04-30
- **Target enrollment:** 382 (ESTIMATED)
- **Last updated:** 2026-05-05

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07100990

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07100990, "Treatment of Inflammatory Myelitis and Optic Neuritis With Early vs Rescue Plasma Exchange (TIMELY-PLEX)". Retrieved via AI Analytics 2026-06-01 from https://api.ai-analytics.org/clinical/NCT07100990. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*