# White Matter Distortion and Dementia Biomarkers in Normal Pressure Hydrocephalus (NPH)

> **NCT07103681** · — · RECRUITING · sponsor: **Imperial College London** · enrollment: 100 (estimated)

## Conditions studied

- Normal Pressure Hydrocephalus

## Interventions

- **PROCEDURE:** Ventriculoperitoneal Shunt (VP)
- **PROCEDURE:** Brain and Skin Biopsy
- **DIAGNOSTIC_TEST:** MRI Brain

## Key facts

- **NCT ID:** NCT07103681
- **Lead sponsor:** Imperial College London
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** RECRUITING
- **Start date:** 2025-03-25
- **Primary completion:** 2028-02
- **Final completion:** 2029-02
- **Target enrollment:** 100 (ESTIMATED)
- **Last updated:** 2026-03-27

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07103681

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07103681, "White Matter Distortion and Dementia Biomarkers in Normal Pressure Hydrocephalus (NPH)". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT07103681. Licensed CC0.

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