TAILORED Therapeutic Regime in Patients With Preterm Premature Rupture Of Membranes to Prolong Pregnancy, Improve Maternal and Neonatal Outcomes, and Reduce Antibiotic Burden

Conditions

• Preterm Premature Rupture of Membranes (PPROM)

Interventions

• PROCEDURE: Tailored antibiotic and steroid therapy based on the IL-6 value in amniotic fluid obtained by amniocentesis in patients with premature rupture of membranes
• DRUG: Antenatal steroids administration
• DRUG: Neuroprotection
• DRUG: antibiotic prophylaxis
• DRUG: Antibiotics administration

Sponsor

The Central and Eastern European Gynecologic Oncology Group

Collaborators

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