# Clinical Study of a Novel Humanized CD70-Targeted CAR-T Cell Incorporating TLR2 for Advanced Renal Cell Carcinoma Therapy

> **NCT07113977** · EARLY_PHASE1 · NOT_YET_RECRUITING · sponsor: **Wei Guan** · enrollment: 30 (estimated)

## Conditions studied

- Advanced Renal Cell Carcinoma

## Interventions

- **BIOLOGICAL:** CAR-T(CD70)

## Key facts

- **NCT ID:** NCT07113977
- **Lead sponsor:** Wei Guan
- **Sponsor class:** OTHER
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2025-08-15
- **Primary completion:** 2028-08-31
- **Final completion:** 2028-12-31
- **Target enrollment:** 30 (ESTIMATED)
- **Last updated:** 2025-08-11


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07113977

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07113977, "Clinical Study of a Novel Humanized CD70-Targeted CAR-T Cell Incorporating TLR2 for Advanced Renal Cell Carcinoma Therapy". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT07113977. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*