# Treatment of Symptomatic Bilateral Knee Osteoarthritis: Intra-articular Injection of Autologous Microfragmented Adipose Tissue and Hyaluronic Acid vs Intra Articular Injection of Autologous Microfragmented Adipose Tissue

> **NCT07121556** · NA · RECRUITING · sponsor: **Istituto Ortopedico Rizzoli** · enrollment: 100 (estimated)

## Conditions studied

- Osteoarthritis Knees Both

## Interventions

- **DEVICE:** MFAT + HA left knee - MFAT + placebo right knee
- **BIOLOGICAL:** MFAT + HA right knee - MFAT + placebo left knee

## Key facts

- **NCT ID:** NCT07121556
- **Lead sponsor:** Istituto Ortopedico Rizzoli
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-09-29
- **Primary completion:** 2030-09
- **Final completion:** 2030-09
- **Target enrollment:** 100 (ESTIMATED)
- **Last updated:** 2025-12-03


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07121556

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07121556, "Treatment of Symptomatic Bilateral Knee Osteoarthritis: Intra-articular Injection of Autologous Microfragmented Adipose Tissue and Hyaluronic Acid vs Intra Articular Injection of Autologous Microfragmented Adipose Tissue". Retrieved via AI Analytics 2026-07-25 from https://api.ai-analytics.org/clinical/NCT07121556. Licensed CC0.

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