# Effect of Intravenous and Topical Tranexamic Acid on Drain Output in Breast Reduction Surgery

> **NCT07131592** · PHASE4 · RECRUITING · sponsor: **Massachusetts General Hospital** · enrollment: 160 (estimated)

## Conditions studied

- Drain Output After Breast Reduction Surgery
- Breast Reductions

## Interventions

- **DRUG:** IV TXA
- **DRUG:** Topical TXA
- **DRUG:** Topical saline

## Key facts

- **NCT ID:** NCT07131592
- **Lead sponsor:** Massachusetts General Hospital
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-11-18
- **Primary completion:** 2027-03-01
- **Final completion:** 2027-08-31
- **Target enrollment:** 160 (ESTIMATED)
- **Last updated:** 2026-01-16


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07131592

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07131592, "Effect of Intravenous and Topical Tranexamic Acid on Drain Output in Breast Reduction Surgery". Retrieved via AI Analytics 2026-07-20 from https://api.ai-analytics.org/clinical/NCT07131592. Licensed CC0.

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