# Clinical Study to Evaluate the Anti-cavity Efficacy of Three Dentifrices: An In Situ Model

> **NCT07134231** · PHASE3 · COMPLETED · sponsor: **Colgate Palmolive** · enrollment: 36 (actual)

## Conditions studied

- Demineralization
- Remineralization
- Dental Cavity
- Enamel Lesions

## Interventions

- **DRUG:** Fluoride free toothpaste in a chalk base
- **DRUG:** Fluoride Toothpaste
- **DRUG:** Fluoride free toothpaste in a PCC/RNCC base
- **DEVICE:** Toothbrush

## Key facts

- **NCT ID:** NCT07134231
- **Lead sponsor:** Colgate Palmolive
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2025-10-09
- **Primary completion:** 2025-12-11
- **Final completion:** 2025-12-11
- **Target enrollment:** 36 (ACTUAL)
- **Last updated:** 2026-02-06

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07134231

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07134231, "Clinical Study to Evaluate the Anti-cavity Efficacy of Three Dentifrices: An In Situ Model". Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/clinical/NCT07134231. Licensed CC0.

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