# A Trial of 2 Disease-Modifying Drugs (Metformin and N-acetylcysteine ) to Promote TB Lung Function Recovery

> **NCT07136987** · PHASE3 · NOT_YET_RECRUITING · sponsor: **Open Source Pharma Foundation** · enrollment: 1104 (estimated)

## Conditions studied

- Tuberculosis

## Interventions

- **DRUG:** Metformin
- **DIETARY_SUPPLEMENT:** N-Acetylcysteine (NAC) Treatment
- **COMBINATION_PRODUCT:** Standard TB treatment

## Key facts

- **NCT ID:** NCT07136987
- **Lead sponsor:** Open Source Pharma Foundation
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-01
- **Primary completion:** 2031-01
- **Final completion:** 2031-07
- **Target enrollment:** 1104 (ESTIMATED)
- **Last updated:** 2025-08-22

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07136987

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07136987, "A Trial of 2 Disease-Modifying Drugs (Metformin and N-acetylcysteine ) to Promote TB Lung Function Recovery". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT07136987. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*