# Hyperthermic Intraperitoneal Chemotherapy With Cisplatin and Paclitaxel for the Treatment of Patients With Gastric and Gastroesophageal Junction Adenocarcinoma at High Risk of Peritoneal Recurrence

> **NCT07139951** · PHASE2 · ENROLLING_BY_INVITATION · sponsor: **Mayo Clinic** · enrollment: 16 (estimated)

## Conditions studied

- Clinical Stage I Gastric Cancer AJCC v8
- Clinical Stage I Gastroesophageal Junction Adenocarcinoma AJCC v8
- Clinical Stage II Gastric Cancer AJCC v8
- Clinical Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8
- Clinical Stage III Gastric Cancer AJCC v8
- Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8
- Gastric Adenocarcinoma
- Gastroesophageal Junction Adenocarcinoma

## Interventions

- **PROCEDURE:** Biopsy Procedure
- **PROCEDURE:** Biospecimen Collection
- **DRUG:** Cisplatin
- **PROCEDURE:** Computed Tomography
- **DRUG:** Hyperthermic Intraperitoneal Chemotherapy
- **PROCEDURE:** Laparoscopy
- **PROCEDURE:** Lymphadenectomy
- **PROCEDURE:** Magnetic Resonance Imaging
- **DRUG:** Paclitaxel
- **PROCEDURE:** Positron Emission Tomography
- **PROCEDURE:** Surgical Procedure

## Key facts

- **NCT ID:** NCT07139951
- **Lead sponsor:** Mayo Clinic
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** ENROLLING_BY_INVITATION
- **Start date:** 2025-12-03
- **Primary completion:** 2027-05-03
- **Final completion:** 2031-11-03
- **Target enrollment:** 16 (ESTIMATED)
- **Last updated:** 2025-12-31


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07139951

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07139951, "Hyperthermic Intraperitoneal Chemotherapy With Cisplatin and Paclitaxel for the Treatment of Patients With Gastric and Gastroesophageal Junction Adenocarcinoma at High Risk of Peritoneal Recurrence". Retrieved via AI Analytics 2026-07-15 from https://api.ai-analytics.org/clinical/NCT07139951. Licensed CC0.

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