# ED50 of Dexmedetomidine as an Adjuvant to 0.5% Hyperbaric Bupivacaine 12.5 mg for Spinal Anesthesia in Hip and Knee Surgery: An Up-and-Down Method Approach

> **NCT07144215** · NA · COMPLETED · sponsor: **Indonesia University** · enrollment: 40 (actual)

## Conditions studied

- Knee Surgery
- Pelvic Surgery
- Spinal Aneshtesia

## Interventions

- **DRUG:** Dexmedetomidine 3 mcg
- **DRUG:** Dexmedetomidine 4 mcg
- **DRUG:** Dexmedetomidine 5 mcg
- **DRUG:** Dexmedetomidine 6 mcg
- **DRUG:** Bupivacain hyperbaric 0.5% 12.5 mg

## Key facts

- **NCT ID:** NCT07144215
- **Lead sponsor:** Indonesia University
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2025-02-01
- **Primary completion:** 2025-05-31
- **Final completion:** 2025-05-31
- **Target enrollment:** 40 (ACTUAL)
- **Last updated:** 2025-09-05


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07144215

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07144215, "ED50 of Dexmedetomidine as an Adjuvant to 0.5% Hyperbaric Bupivacaine 12.5 mg for Spinal Anesthesia in Hip and Knee Surgery: An Up-and-Down Method Approach". Retrieved via AI Analytics 2026-06-12 from https://api.ai-analytics.org/clinical/NCT07144215. Licensed CC0.

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