Immunotherapy for Solid Tumor Malignancies in Pediatrics Using Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor T Cells

NCT07148050 · clinicaltrials.gov ↗

PHASE1

Phase

RECRUITING

Status

21

Enrollment

OTHER

Sponsor class

Conditions

Solid Tumor (Excluding CNS)
Liver Cell Carcinoma
Malignant Rhabdoid Tumor
Yolk Sac Tumor
Liposarcoma
Rhabdomyosarcoma
Embryonal Sarcoma of Liver
Wilms Tumor
Hepatocellular Carcinoma
Hepatoblastoma

Interventions

BIOLOGICAL: SC-CAR.GPC3xIL15.21 CAR T cells

Sponsor

Seattle Children's Hospital