# Electrophysiologist-led Deep Sedation Protocols for Pulsed Field Ablation for Atrial Fibrillation Using a Bipolar Tip-Catheter: The DEEP-PFA Randomized Controlled Trial

> **NCT07149545** · NA · COMPLETED · sponsor: **Beijing Anzhen Hospital** · enrollment: 240 (actual)

## Conditions studied

- Atrial Fibrillation (AF)
- PFA
- Deep Sedation

## Interventions

- **DRUG:** Arm A (Fentanyl + Midazolam)
- **DRUG:** Arm B (Flurbiprofen axetil + Fentanyl + Midazolam)
- **DRUG:** Arm C (Fentanyl + Dexmedetomidine)

## Key facts

- **NCT ID:** NCT07149545
- **Lead sponsor:** Beijing Anzhen Hospital
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2025-10-15
- **Primary completion:** 2026-01-27
- **Final completion:** 2026-01-27
- **Target enrollment:** 240 (ACTUAL)
- **Last updated:** 2026-02-11


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07149545

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07149545, "Electrophysiologist-led Deep Sedation Protocols for Pulsed Field Ablation for Atrial Fibrillation Using a Bipolar Tip-Catheter: The DEEP-PFA Randomized Controlled Trial". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT07149545. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*