# Efficacy And Safety Of Tramadol And Oxycodone Versus Oxycodone Monotherapy For Pain Control After Primary Total Knee And Total Hip Arthroplasty

> **NCT07153003** · PHASE4 · ENROLLING_BY_INVITATION · sponsor: **Mayo Clinic** · enrollment: 560 (estimated)

## Conditions studied

- Post Operative Pain

## Interventions

- **DRUG:** Oxycodone
- **DRUG:** Tramadol and Oxycodone

## Key facts

- **NCT ID:** NCT07153003
- **Lead sponsor:** Mayo Clinic
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** ENROLLING_BY_INVITATION
- **Start date:** 2026-02-02
- **Primary completion:** 2030-09-01
- **Final completion:** 2031-09-01
- **Target enrollment:** 560 (ESTIMATED)
- **Last updated:** 2026-03-18


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07153003

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07153003, "Efficacy And Safety Of Tramadol And Oxycodone Versus Oxycodone Monotherapy For Pain Control After Primary Total Knee And Total Hip Arthroplasty". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT07153003. Licensed CC0.

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