# Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of PN-881 in Healthy Subjects.

> **NCT07153146** · PHASE1 · RECRUITING · sponsor: **Protagonist Therapeutics, Inc.** · enrollment: 142 (estimated)

## Conditions studied

- Healthy Volunteer

## Interventions

- **DRUG:** PN-881 Oral Solution
- **DRUG:** PN-881 Oral Tablet
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT07153146
- **Lead sponsor:** Protagonist Therapeutics, Inc.
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-10-07
- **Primary completion:** 2026-06-15
- **Final completion:** 2026-06-15
- **Target enrollment:** 142 (ESTIMATED)
- **Last updated:** 2025-12-16


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07153146

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07153146, "Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of PN-881 in Healthy Subjects.". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT07153146. Licensed CC0.

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