# Comparison of Esketamine Nasal Spray vs.Aripiprazole in Treat.Resistant Major Depressive Disorder in Elderly Patients

> **NCT07153406** · PHASE3 · NOT_YET_RECRUITING · sponsor: **Fundación Pública Andaluza para la gestión de la Investigación en Sevilla** · enrollment: 220 (estimated)

## Conditions studied

- Depressive Disorder

## Interventions

- **DRUG:** Experimental regimen
- **DRUG:** Control regimen

## Key facts

- **NCT ID:** NCT07153406
- **Lead sponsor:** Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2025-09-15
- **Primary completion:** 2026-09-15
- **Final completion:** 2029-01-15
- **Target enrollment:** 220 (ESTIMATED)
- **Last updated:** 2025-09-04


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07153406

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07153406, "Comparison of Esketamine Nasal Spray vs.Aripiprazole in Treat.Resistant Major Depressive Disorder in Elderly Patients". Retrieved via AI Analytics 2026-06-01 from https://api.ai-analytics.org/clinical/NCT07153406. Licensed CC0.

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