# Phase II RCT of LCRT vs SCRT + CAPOX/PD-1i/COX-2i in MSS Locally Advanced Rectal Cancer

> **NCT07154316** · PHASE2 · RECRUITING · sponsor: **Fudan University** · enrollment: 138 (estimated)

## Conditions studied

- Colorectal Cancer

## Interventions

- **RADIATION:** LCRT
- **RADIATION:** SCRT
- **DRUG:** CAPOX
- **DRUG:** PD-1
- **DRUG:** Celecoxib

## Key facts

- **NCT ID:** NCT07154316
- **Lead sponsor:** Fudan University
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-08-01
- **Primary completion:** 2028-08-01
- **Final completion:** 2028-12-30
- **Target enrollment:** 138 (ESTIMATED)
- **Last updated:** 2025-09-04

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07154316

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07154316, "Phase II RCT of LCRT vs SCRT + CAPOX/PD-1i/COX-2i in MSS Locally Advanced Rectal Cancer". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT07154316. Licensed CC0.

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