# Investigating the Safety and Regenerative Potential of MSC-Derived Secretome Combined With PRGF in Knee Osteoarthritis

> **NCT07157891** · EARLY_PHASE1 · NOT_YET_RECRUITING · sponsor: **University of the Punjab** · enrollment: 25 (estimated)

## Conditions studied

- Osteoarthritis (OA)
- Knee Injury
- Cartilage Degeneration

## Interventions

- **BIOLOGICAL:** MSC-Derived Secretome
- **BIOLOGICAL:** MSC-Derived Secretome + Autologous PRGF

## Key facts

- **NCT ID:** NCT07157891
- **Lead sponsor:** University of the Punjab
- **Sponsor class:** OTHER
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2025-12-10
- **Primary completion:** 2027-12-11
- **Final completion:** 2028-12-11
- **Target enrollment:** 25 (ESTIMATED)
- **Last updated:** 2025-09-05

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07157891

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07157891, "Investigating the Safety and Regenerative Potential of MSC-Derived Secretome Combined With PRGF in Knee Osteoarthritis". Retrieved via AI Analytics 2026-06-23 from https://api.ai-analytics.org/clinical/NCT07157891. Licensed CC0.

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