# Role of Methotrexate in Ultrasound Proven Synovitis in Primary Knee OA

> **NCT07161336** · PHASE2 · RECRUITING · sponsor: **Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh** · enrollment: 70 (estimated)

## Conditions studied

- Osteo Arthritis of the Knee
- Synovitis of Knee
- Methotrexate

## Interventions

- **DRUG:** Methotrexate (MTX)
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT07161336
- **Lead sponsor:** Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-07-30
- **Primary completion:** 2026-07-01
- **Final completion:** 2026-08-30
- **Target enrollment:** 70 (ESTIMATED)
- **Last updated:** 2025-09-12


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07161336

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07161336, "Role of Methotrexate in Ultrasound Proven Synovitis in Primary Knee OA". Retrieved via AI Analytics 2026-06-03 from https://api.ai-analytics.org/clinical/NCT07161336. Licensed CC0.

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