# Effects of PFO Closure on Glymphatic Function and Clinical Symptoms in Patients With Migraine

> **NCT07170176** · NA · RECRUITING · sponsor: **First Affiliated Hospital Xi'an Jiaotong University** · enrollment: 150 (estimated)

## Conditions studied

- Migraine Disorders
- Patent Foramen Ovale
- Right-to-Left Shunt, Cardiac

## Interventions

- **DEVICE:** Percutaneous Patent Foramen Ovale Closure
- **OTHER:** No Intervention

## Key facts

- **NCT ID:** NCT07170176
- **Lead sponsor:** First Affiliated Hospital Xi'an Jiaotong University
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2026-01-14
- **Primary completion:** 2027-05-31
- **Final completion:** 2027-12-31
- **Target enrollment:** 150 (ESTIMATED)
- **Last updated:** 2026-01-16


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07170176

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07170176, "Effects of PFO Closure on Glymphatic Function and Clinical Symptoms in Patients With Migraine". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT07170176. Licensed CC0.

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