# Clinical Trial of Neoadjuvant mFOLFOX Plus Alvenor for LARC Patients With High YWHAB Expression

> **NCT07176182** · PHASE2 · NOT_YET_RECRUITING · sponsor: **Sixth Affiliated Hospital, Sun Yat-sen University** · enrollment: 236 (estimated)

## Conditions studied

- Rectal Cancer Patients
- Rectal Cancer Stage II
- Rectal Cancer Stage III

## Interventions

- **DRUG:** mFOLFOX regimen combined with Citrus Flavone Tablets (Alvenor) neoadjuvant treatment group
- **DRUG:** mFOLFOX regimen neoadjuvant therapy group

## Key facts

- **NCT ID:** NCT07176182
- **Lead sponsor:** Sixth Affiliated Hospital, Sun Yat-sen University
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-03-01
- **Primary completion:** 2031-03-01
- **Final completion:** 2031-03-01
- **Target enrollment:** 236 (ESTIMATED)
- **Last updated:** 2026-02-27

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07176182

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07176182, "Clinical Trial of Neoadjuvant mFOLFOX Plus Alvenor for LARC Patients With High YWHAB Expression". Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/clinical/NCT07176182. Licensed CC0.

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