# Azithromycin and Ampicillin for Late PPROM

> **NCT07183462** · PHASE4 · RECRUITING · sponsor: **Sheba Medical Center** · enrollment: 311 (estimated)

## Conditions studied

- Pregnancy Complications, Infectious
- Premature Birth
- Neonatal Diseases and Abnormalities
- Antibiotic Prophylaxis
- Latency Period
- Prematurity

## Interventions

- **DRUG:** Intravenous Ampicillin followed by Oral Amoxicillin
- **DRUG:** Ampicillin/Amoxicillin plus single-dose PO Azithromycin

## Key facts

- **NCT ID:** NCT07183462
- **Lead sponsor:** Sheba Medical Center
- **Sponsor class:** OTHER_GOV
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-09-10
- **Primary completion:** 2029-06-30
- **Final completion:** 2029-07-31
- **Target enrollment:** 311 (ESTIMATED)
- **Last updated:** 2025-12-18


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07183462

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07183462, "Azithromycin and Ampicillin for Late PPROM". Retrieved via AI Analytics 2026-06-30 from https://api.ai-analytics.org/clinical/NCT07183462. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*