# Efficacy and Safety of Low-Dose Cytarabine Combined With Thalidomide in Adult Patients With Untreated LCH

> **NCT07187193** · PHASE2 · RECRUITING · sponsor: **Cancer Institute and Hospital, Chinese Academy of Medical Sciences** · enrollment: 50 (estimated)

## Conditions studied

- Langerhans Cell Histiocytosis

## Interventions

- **DRUG:** Cytarabine (Ara-C)
- **DRUG:** Thalidomide (100mg)

## Key facts

- **NCT ID:** NCT07187193
- **Lead sponsor:** Cancer Institute and Hospital, Chinese Academy of Medical Sciences
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-04-12
- **Primary completion:** 2027-04-12
- **Final completion:** 2027-04-13
- **Target enrollment:** 50 (ESTIMATED)
- **Last updated:** 2025-09-22


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07187193

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07187193, "Efficacy and Safety of Low-Dose Cytarabine Combined With Thalidomide in Adult Patients With Untreated LCH". Retrieved via AI Analytics 2026-06-16 from https://api.ai-analytics.org/clinical/NCT07187193. Licensed CC0.

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