# The Impact of Low Versus High Positive End-expiratory Pressure on Diaphragm Function, Ventilation Efficiency, and Lung Mechanics

> **NCT07188038** · NA · NOT_YET_RECRUITING · sponsor: **Vastra Gotaland Region** · enrollment: 25 (estimated)

## Conditions studied

- Respiratory Failure
- ARDS (Acute Respiratory Distress Syndrome)
- Pneumonia
- Respiratory Insufficiency

## Interventions

- **PROCEDURE:** Low positive end-expiratory pressure
- **PROCEDURE:** Medium positive end-expiratory pressure
- **PROCEDURE:** High positive end-expiratory pressure

## Key facts

- **NCT ID:** NCT07188038
- **Lead sponsor:** Vastra Gotaland Region
- **Sponsor class:** OTHER_GOV
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2025-10-01
- **Primary completion:** 2027-07-31
- **Final completion:** 2027-12-31
- **Target enrollment:** 25 (ESTIMATED)
- **Last updated:** 2025-09-23

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07188038

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07188038, "The Impact of Low Versus High Positive End-expiratory Pressure on Diaphragm Function, Ventilation Efficiency, and Lung Mechanics". Retrieved via AI Analytics 2026-07-20 from https://api.ai-analytics.org/clinical/NCT07188038. Licensed CC0.

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