# CReep and Maintenance flUid Sodium Chloride ADministration rEduction in cRitically Ill adultS

> **NCT07189091** · PHASE4 · RECRUITING · sponsor: **University Hospital, Antwerp** · enrollment: 640 (estimated)

## Conditions studied

- Critical Care, Intensive Care
- Fluid Accumulation
- Fluid and Electrolyte Imbalance
- Critical Illness
- Fluid Balance Outcomes

## Interventions

- **DRUG:** Glucose 5% for fluid creep
- **DRUG:** NaCl 0.9% (normal saline) for fluid creep
- **DRUG:** PlasmaLyte as maintenance fluid
- **DRUG:** NaCl 0.3% in glucose 3.3% as maintenance fluid

## Key facts

- **NCT ID:** NCT07189091
- **Lead sponsor:** University Hospital, Antwerp
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-10-07
- **Primary completion:** 2028-04-30
- **Final completion:** 2028-07-30
- **Target enrollment:** 640 (ESTIMATED)
- **Last updated:** 2026-02-03

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07189091

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07189091, "CReep and Maintenance flUid Sodium Chloride ADministration rEduction in cRitically Ill adultS". Retrieved via AI Analytics 2026-06-23 from https://api.ai-analytics.org/clinical/NCT07189091. Licensed CC0.

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