# Clinical Study of Chemotherapy and Immunotherapy Combined With Lactobacillus Johnsonii in Patients With Multiple Irresectable Solid Tumors

> **NCT07191405** · NA · NOT_YET_RECRUITING · sponsor: **Second Affiliated Hospital, School of Medicine, Zhejiang University** · enrollment: 156 (estimated)

## Conditions studied

- Immunotherapy
- Chemotherapy

## Interventions

- **DIETARY_SUPPLEMENT:** oral Lactobacillus johnsonii (1×10¹¹ CFU, twice daily)
- **DIETARY_SUPPLEMENT:** Placebo

## Key facts

- **NCT ID:** NCT07191405
- **Lead sponsor:** Second Affiliated Hospital, School of Medicine, Zhejiang University
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2025-09-18
- **Primary completion:** 2026-07-01
- **Final completion:** 2026-12-31
- **Target enrollment:** 156 (ESTIMATED)
- **Last updated:** 2025-09-24


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07191405

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07191405, "Clinical Study of Chemotherapy and Immunotherapy Combined With Lactobacillus Johnsonii in Patients With Multiple Irresectable Solid Tumors". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT07191405. Licensed CC0.

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