# Stupp Treatment With Intrathecal Injection of Thiotepa for Glioblastoma With Advanced Spread

> **NCT07193654** · PHASE2 · RECRUITING · sponsor: **Second Affiliated Hospital, School of Medicine, Zhejiang University** · enrollment: 38 (estimated)

## Conditions studied

- Glioblastoma (GBM)

## Interventions

- **DRUG:** Intrathecal injection of thiotepa
- **DRUG:** Stupp regimen (oral temozolomide)
- **RADIATION:** Radical radiotherapy
- **PROCEDURE:** Maximal surgical resection

## Key facts

- **NCT ID:** NCT07193654
- **Lead sponsor:** Second Affiliated Hospital, School of Medicine, Zhejiang University
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-04-01
- **Primary completion:** 2027-04-01
- **Final completion:** 2028-04-01
- **Target enrollment:** 38 (ESTIMATED)
- **Last updated:** 2025-09-26


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07193654

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07193654, "Stupp Treatment With Intrathecal Injection of Thiotepa for Glioblastoma With Advanced Spread". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT07193654. Licensed CC0.

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