# Influence of Personalized Lung Volume Optimization Maneuver on Lung Function and Cardiac Performance in Children

> **NCT07193719** · PHASE1,PHASE2 · RECRUITING · sponsor: **Charite University, Berlin, Germany** · enrollment: 80 (estimated)

## Conditions studied

- Congenital Heart Disease
- Cardiopulmonary Bypass
- Cardiac Surgery
- Mechanical Ventilation
- Positive End-expiratory Pressure (PEEP)
- Lung Volume
- Lung Mechanics
- Hemodynamic Changes
- Children
- ARDS
- ECMO

## Interventions

- **PROCEDURE:** End-expiratory lung volume optimization maneuver with PEEP titration
- **PROCEDURE:** Standard Care (in control arm)

## Key facts

- **NCT ID:** NCT07193719
- **Lead sponsor:** Charite University, Berlin, Germany
- **Sponsor class:** OTHER
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-12-05
- **Primary completion:** 2027-05-31
- **Final completion:** 2027-12-20
- **Target enrollment:** 80 (ESTIMATED)
- **Last updated:** 2026-04-09


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07193719

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07193719, "Influence of Personalized Lung Volume Optimization Maneuver on Lung Function and Cardiac Performance in Children". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT07193719. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*