# Drug-Drug Interaction of Rifampicin and Cyclosporine on Methotrexate Pharmacokinetics in Healthy Subjects

> **NCT07196449** · PHASE1 · ACTIVE_NOT_RECRUITING · sponsor: **Seoul National University Bundang Hospital** · enrollment: 12 (actual)

## Conditions studied

- Drug Drug Interaction (DDI)

## Interventions

- **DRUG:** Methotrexate
- **DRUG:** Rifampicin
- **DRUG:** Cyclosporine

## Key facts

- **NCT ID:** NCT07196449
- **Lead sponsor:** Seoul National University Bundang Hospital
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2025-05-14
- **Primary completion:** 2025-06-09
- **Final completion:** 2026-04-14
- **Target enrollment:** 12 (ACTUAL)
- **Last updated:** 2025-09-29


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07196449

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07196449, "Drug-Drug Interaction of Rifampicin and Cyclosporine on Methotrexate Pharmacokinetics in Healthy Subjects". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT07196449. Licensed CC0.

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