# CYFIP1 and PKM2 Synergistically Regulate ROS and Glycolysis in Colorectal Cancer Through the AKT/mTOR/HIF-1α Cascad

> **NCT07197151** · — · COMPLETED · sponsor: **hui hou** · enrollment: 32 (actual)

## Conditions studied

- Colorectal Cancer (CRC)
- Specimens Are to be Collected From Subjects Who Are Having or Have Had a Fluid or Tissue Removed, a Biopsy or a Blood or Bone Marrow Draw

## Interventions

- **OTHER:** Perform surgery on patients with colorectal cancer and collect cancer and adjacent tissue specimens

## Key facts

- **NCT ID:** NCT07197151
- **Lead sponsor:** hui hou
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** COMPLETED
- **Start date:** 2022-08-01
- **Primary completion:** 2025-09-01
- **Final completion:** 2025-09-01
- **Target enrollment:** 32 (ACTUAL)
- **Last updated:** 2025-09-29


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07197151

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07197151, "CYFIP1 and PKM2 Synergistically Regulate ROS and Glycolysis in Colorectal Cancer Through the AKT/mTOR/HIF-1α Cascad". Retrieved via AI Analytics 2026-06-23 from https://api.ai-analytics.org/clinical/NCT07197151. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*
