# Comparative Efficacy and Safety of Acetazolamide Versus Metolazone as an Adjunct to Standard Therapy in Patients With Acute Decompensated Heart Failure

> **NCT07199088** · NA · RECRUITING · sponsor: **University of Health Sciences Lahore** · enrollment: 320 (estimated)

## Conditions studied

- Acute Decompensated Heart Failure
- Heart Failure, Diastolic
- Heart Failure, Systolic

## Interventions

- **OTHER:** Acetazolamide
- **OTHER:** Metolazone

## Key facts

- **NCT ID:** NCT07199088
- **Lead sponsor:** University of Health Sciences Lahore
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-10-11
- **Primary completion:** 2026-10-16
- **Final completion:** 2026-10-30
- **Target enrollment:** 320 (ESTIMATED)
- **Last updated:** 2025-10-03


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07199088

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07199088, "Comparative Efficacy and Safety of Acetazolamide Versus Metolazone as an Adjunct to Standard Therapy in Patients With Acute Decompensated Heart Failure". Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/clinical/NCT07199088. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*