Allogeneic, Antigen-Presenting, GM-CSF-secreting, SV-BR-1-GM Whole Cell-Therapeutic Vaccine and Immunotherapy: A Phase I Pilot Safety and Feasibility Study for Solid Tumor Patients With CNS Metastases

NCT07199413 · clinicaltrials.gov ↗

PHASE1

Phase

NOT_YET_RECRUITING

Status

20

Enrollment

OTHER

Sponsor class

Conditions

Brain Metastases
Leptomeningeal Metastasis

Interventions

BIOLOGICAL: SV-BR-1-GM Vaccine
DRUG: Cyclophosphamide
DRUG: Pembrolizumab
DRUG: Interferon

Sponsor

Medical College of Wisconsin