# The Role of Estrogen and Testosterone in Determining Brain Blood Flow and Metabolic Regulation in Humans

> **NCT07212712** · NA · NOT_YET_RECRUITING · sponsor: **University of British Columbia** · enrollment: 50 (estimated)

## Conditions studied

- Cerebral Blood Flow
- Cerebral Blood Flow Regulation
- Sex Differences
- Exercise
- Vascular

## Interventions

- **DRUG:** GnRH antagonist
- **DRUG:** Estradiol (E2)
- **DRUG:** Testosterone
- **DRUG:** Anastrozole (Arimidex)

## Key facts

- **NCT ID:** NCT07212712
- **Lead sponsor:** University of British Columbia
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-04-01
- **Primary completion:** 2026-12-31
- **Final completion:** 2027-12-31
- **Target enrollment:** 50 (ESTIMATED)
- **Last updated:** 2026-02-10


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07212712

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07212712, "The Role of Estrogen and Testosterone in Determining Brain Blood Flow and Metabolic Regulation in Humans". Retrieved via AI Analytics 2026-07-12 from https://api.ai-analytics.org/clinical/NCT07212712. Licensed CC0.

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