# Venetoclax and Obinutuzumab Followed by Epcoritamab for the Treatment of Untreated Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma, LonGEVity Trial

> **NCT07218510** · PHASE2 · RECRUITING · sponsor: **City of Hope Medical Center** · enrollment: 33 (estimated)

## Conditions studied

- Chronic Lymphocytic Leukemia
- Small Lymphocytic Lymphoma

## Interventions

- **PROCEDURE:** Biospecimen Collection
- **PROCEDURE:** Bone Marrow Aspiration
- **PROCEDURE:** Bone Marrow Biopsy
- **PROCEDURE:** Computed Tomography
- **OTHER:** Electronic Health Record Review
- **BIOLOGICAL:** Epcoritamab
- **PROCEDURE:** Magnetic Resonance Imaging
- **BIOLOGICAL:** Obinutuzumab
- **DRUG:** Venetoclax

## Key facts

- **NCT ID:** NCT07218510
- **Lead sponsor:** City of Hope Medical Center
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2026-01-07
- **Primary completion:** 2029-06-08
- **Final completion:** 2029-06-08
- **Target enrollment:** 33 (ESTIMATED)
- **Last updated:** 2026-03-13

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07218510

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07218510, "Venetoclax and Obinutuzumab Followed by Epcoritamab for the Treatment of Untreated Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma, LonGEVity Trial". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT07218510. Licensed CC0.

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