# Evaluation of the Safety and Effects of Psychoactive Substances in People With Past Opioid Use

> **NCT07218549** · PHASE1 · NOT_YET_RECRUITING · sponsor: **Christopher D. Verrico** · enrollment: 72 (estimated)

## Conditions studied

- Opioid Use
- Substance Use Disorders
- Opioid Analgesia

## Interventions

- **DRUG:** Placebo
- **DRUG:** Oxycodone HCl
- **DRUG:** Kratom 8g
- **DRUG:** Kratom 12g
- **DRUG:** Kratom 16g
- **DRUG:** Kratom 4g

## Key facts

- **NCT ID:** NCT07218549
- **Lead sponsor:** Christopher D. Verrico
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-05-01
- **Primary completion:** 2028-12-31
- **Final completion:** 2029-05-31
- **Target enrollment:** 72 (ESTIMATED)
- **Last updated:** 2026-03-13

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07218549

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07218549, "Evaluation of the Safety and Effects of Psychoactive Substances in People With Past Opioid Use". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT07218549. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*