# Oral Methadone in Cardiac Surgery

> **NCT07221617** · PHASE4 · RECRUITING · sponsor: **Mayo Clinic** · enrollment: 100 (estimated)

## Conditions studied

- Pain, Postoperative
- Anesthesia
- Cardiac Surgery

## Interventions

- **DRUG:** Methadone, oral
- **DRUG:** Methadone, intravenously

## Key facts

- **NCT ID:** NCT07221617
- **Lead sponsor:** Mayo Clinic
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2026-01-13
- **Primary completion:** 2026-06-30
- **Final completion:** 2026-08
- **Target enrollment:** 100 (ESTIMATED)
- **Last updated:** 2026-01-14


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07221617

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07221617, "Oral Methadone in Cardiac Surgery". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT07221617. Licensed CC0.

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