Dose-Adjusted EPOCH With or Without Rituximab Plus Ponatinib for the Treatment of Newly-Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia/Lymphoma

NCT07224100 · clinicaltrials.gov ↗

PHASE2

Phase

RECRUITING

Status

33

Enrollment

OTHER

Sponsor class

Conditions

B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1
B Lymphoblastic Leukemia/Lymphoma With t(9;22)(q34.1;q11.2); BCR-ABL1
Lymphoblastic Lymphoma

Interventions

DRUG: Cyclophosphamide
DRUG: Doxorubicin
DRUG: Etoposide
BIOLOGICAL: Filgrastim
BIOLOGICAL: Pegfilgrastim
DRUG: Ponatinib
DRUG: Prednisone
BIOLOGICAL: Rituximab
DRUG: Vincristine
PROCEDURE: Biospecimen Collection
PROCEDURE: Bone Marrow Aspiration
PROCEDURE: Bone Marrow Biopsy
PROCEDURE: Computed Tomography
PROCEDURE: Positron Emission Tomography

Sponsor

University of Washington

Collaborators

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