# Cardiovascular and Renal Endpoints With Flozins - an Observational Prospective Study in CKD HFpEF Patients

> **NCT07237451** · — · RECRUITING · sponsor: **Grigore T. Popa University of Medicine and Pharmacy** · enrollment: 200 (estimated)

## Conditions studied

- CKD - Chronic Kidney Disease
- Heart Failure Preserved Ejection Fraction
- SGLT2 Inhibitors
- Diabetes (DM)

## Interventions

- **DIAGNOSTIC_TEST:** Arterial stiffness
- **DIAGNOSTIC_TEST:** Echocardiography
- **OTHER:** Biomarkers determination
- **OTHER:** NMR metabolomics and uremic toxins mapping

## Key facts

- **NCT ID:** NCT07237451
- **Lead sponsor:** Grigore T. Popa University of Medicine and Pharmacy
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** RECRUITING
- **Start date:** 2025-01-08
- **Primary completion:** 2027-03-01
- **Final completion:** 2027-12-31
- **Target enrollment:** 200 (ESTIMATED)
- **Last updated:** 2025-11-19

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07237451

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07237451, "Cardiovascular and Renal Endpoints With Flozins - an Observational Prospective Study in CKD HFpEF Patients". Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/clinical/NCT07237451. Licensed CC0.

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