# Exploring Sympathetic Nervous System Function in Individuals With Down Syndrome

> **NCT07238465** · PHASE3 · RECRUITING · sponsor: **University of Colorado, Denver** · enrollment: 200 (estimated)

## Conditions studied

- Down Syndrome
- Autonomic Dysfunction

## Interventions

- **OTHER:** Fear Response
- **OTHER:** Cold Stress
- **OTHER:** Pain Response
- **OTHER:** Caffeine
- **OTHER:** 12-Hour Fast
- **OTHER:** Maximal Dynamic Exercise

## Key facts

- **NCT ID:** NCT07238465
- **Lead sponsor:** University of Colorado, Denver
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2026-04-06
- **Primary completion:** 2028-12
- **Final completion:** 2029-12
- **Target enrollment:** 200 (ESTIMATED)
- **Last updated:** 2026-05-04

## Collaborators

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- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07238465

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07238465, "Exploring Sympathetic Nervous System Function in Individuals With Down Syndrome". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT07238465. Licensed CC0.

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