# Relapsed and Progressive Sonic Hedgehog Medulloblastoma With U1 Mutation Registry Study

> **NCT07242963** · — · RECRUITING · sponsor: **Mohammad H. Abu Arja** · enrollment: 300 (estimated)

## Conditions studied

- Medulloblastoma Recurrent
- Medulloblastoma, Childhood, Recurrent
- Medulloblastoma, SHH-activated and TP53 Mutant
- Medulloblastoma, SHH-activated and TP53 Wildtype

## Interventions

_None listed._

## Key facts

- **NCT ID:** NCT07242963
- **Lead sponsor:** Mohammad H. Abu Arja
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** RECRUITING
- **Start date:** 2025-09-30
- **Primary completion:** 2035-12-30
- **Final completion:** 2035-12-30
- **Target enrollment:** 300 (ESTIMATED)
- **Last updated:** 2026-04-13

## Collaborators

- Baylor College of Medicine
- M.D. Anderson Cancer Center

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07242963

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07242963, "Relapsed and Progressive Sonic Hedgehog Medulloblastoma With U1 Mutation Registry Study". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT07242963. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*