# N-acetylcysteine for Root Canal Treatment of Necrotic Teeth With Apical Periodontitis

> **NCT07262554** · PHASE2 · ACTIVE_NOT_RECRUITING · sponsor: **Alexandria University** · enrollment: 40 (estimated)

## Conditions studied

- Apical Periodontitis

## Interventions

- **DRUG:** Calcium hydroxide (Ca(OH)₂)
- **DRUG:** N-Acetylcysteine (NAC)

## Key facts

- **NCT ID:** NCT07262554
- **Lead sponsor:** Alexandria University
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2025-11-15
- **Primary completion:** 2026-06
- **Final completion:** 2026-06
- **Target enrollment:** 40 (ESTIMATED)
- **Last updated:** 2025-12-30


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07262554

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07262554, "N-acetylcysteine for Root Canal Treatment of Necrotic Teeth With Apical Periodontitis". Retrieved via AI Analytics 2026-06-10 from https://api.ai-analytics.org/clinical/NCT07262554. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*