# Comparative Study Evaluating Safety and Effectiveness of ( Proton Pump Inhibitor Versus Vonoprazan ) Based Triple Therapy With or Without Zinc to Eradicate H. Pylori Infection

> **NCT07275827** · PHASE3 · NOT_YET_RECRUITING · sponsor: **Tanta University** · enrollment: 88 (estimated)

## Conditions studied

- HELICOBACTER PYLORI INFECTIONS

## Interventions

- **DRUG:** zinc sulfate
- **DRUG:** Vonoprazan + amoxicillin + clarithromycin
- **DRUG:** proton pump inhibitor + amoxicillin

## Key facts

- **NCT ID:** NCT07275827
- **Lead sponsor:** Tanta University
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-02-01
- **Primary completion:** 2026-04
- **Final completion:** 2026-10
- **Target enrollment:** 88 (ESTIMATED)
- **Last updated:** 2025-12-24


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07275827

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07275827, "Comparative Study Evaluating Safety and Effectiveness of ( Proton Pump Inhibitor Versus Vonoprazan ) Based Triple Therapy With or Without Zinc to Eradicate H. Pylori Infection". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT07275827. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*